Chronic Fatigue May Be Due To Overactive Immune System


Researchers measured fatigue amid immune activity in 55 patients receiving hepatitis C treatment with interpheron-alpha.

By: Erick Sandoval

A study has been found that Chronic Fatigue syndrome, a condition that causes extreme tiredness, could be triggered by an overactive immune system. The study is the first to shed some light into the immunes system’s role in the development of the condition, a multi system disorder that is not very well known. The lead researcher was Carmine Pariante, who is a professor of biological psychiatry at King’s College London.

Pariante also explained that in a lot of cases, patients remember an infection, like a cold or other viral infection, in the early stages of developing the condition. He said “We had this information for quite a long time but didn’t know what was going on in the body of these patients.” Around 250,000 people in the UK and 17 million are affected worldwide by chronic fatigue, according to British charity Action on ME. An estimated 836,000 to 2.5 million Americans struggle with the syndrome. Interpheron Alpha also affects the immune system in a similar way to a strong infection. Researchers measured fatigue amid immune activity in 55 patients receiving hepatitis C treatment with interpheron-alpha.

Patients are often diagnosed with chronic fatigue five, six or even up to years later, according to Patiente. The diagnosis is based entirely on symptoms, such as headaches, difficulty concentrating and the inability to engage in activities.

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